Investigating the relationship between the RET receptor, Cbl and ARHGEF7 in downregulation of RET
The RET proto-oncogene encodes a receptor tyrosine kinase (RTK), with two major isoforms, RET9 and RET51, which differ in their C-termini, and therefore recruit different signaling complexes. RET plays an important role in cell growth, differentiation, migration and survival. Regulation of RET is cr...
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Format: | Others |
Language: | en en |
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2008
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Online Access: | http://hdl.handle.net/1974/1313 |