A Mechanistic Study in Methanol: Cleavage of RNA Models and Highly Stable Phosphodiesters with Dinuclear Zn(II) Complexes

Phosphoryl transfer reactions are vital to life. In response to the slow intrinsic rates of phosphoryl transfer, Nature has evolved a series of enzymes designed to accelerate these reactions and allow them to occur at biologically relevant rates. These metallo-enzymes are largely characterized by bi...

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Bibliographic Details
Main Author: Melnychuk, Stephanie
Other Authors: Queen's University (Kingston, Ont.). Theses (Queen's University (Kingston, Ont.))
Format: Others
Language:en
en
Published: 2008
Subjects:
Online Access:http://hdl.handle.net/1974/1432