CALPAIN: TRANSITIONING FROM THE USE OF THE PROTEASE CORE TO THE FULL-LENGTH ENZYME FOR THE DEVELOPMENT OF SPECIFIC SUBSTRATES AND INHIBITORS
Calpains are a family of calcium-dependent cysteine proteases involved in intracellular signaling. They participate in many normal cellular processes such as cell motility and apoptosis but when over-activated they contribute to diseases ranging from ischemic injury to neurodegenerative disorders....
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| Format: | Others |
| Language: | en en |
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2008
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| Online Access: | http://hdl.handle.net/1974/1489 |