APPLICATION OF CYSTEINE SCANNING MUTAGENESIS TO THE MULTIDRUG RESISTANCE PROTEIN (MRP)1

Multidrug resistance protein (MRP)1, a member of the ABCC branch of the ATP-binding cassette (ABC) superfamily of transporters, can confer resistance to a broad spectrum of chemotherapeutic agents. In addition to the core functional unit of ABC transporters that consists of two membrane spanning do...

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Bibliographic Details
Main Author: Theis, ASHLEY
Other Authors: Queen's University (Kingston, Ont.). Theses (Queen's University (Kingston, Ont.))
Format: Others
Language:en
en
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/1974/1709