The effects of small molecule heme oxygenase inhibitors on rat cytochromes P450 2E1 and 3A1/2
Heme oxygenases (HO) catalyze the degradation of heme into biliverdin, carbon monoxide (CO) and free iron. The two major isoforms, HO-2 (constitutive) and HO-1 (inducible by various stressors such as heavy metals and reactive oxygen species) are involved in a variety of physiological functions, inc...
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| Format: | Others |
| Language: | en en |
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2008
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| Online Access: | http://hdl.handle.net/1974/5321 |