Mechanisms of Amiodarone and Desethylamiodarone Cytotoxicity in Human Lung Cells
Amiodarone (AM) is a potent antidysrhythmic agent which can cause potentially life-threatening pulmonary fibrosis, and N-desethylamiodarone (DEA) is a metabolite of AM that may contribute to the toxicity of AM in vivo. Recent evidence has implicated the involvement of the renin-angiotensin system (...
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Format: | Others |
Language: | en en |
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2009
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Online Access: | http://hdl.handle.net/1974/5334 |