Chalcogenopyrylium Dyes as Modulators of Multidrug Resistance Protein (MRP) 1, MRP2 and MRP4 Transport Activities
MRPs mediate the ATP-dependent efflux of a structurally diverse array of compounds. Certain MRPs, including MRP1, MRP2 and MRP4, are involved in multidrug resistance in tumour cells, while in non-malignant cells these MRPs can influence the distribution and/or elimination of many clinically importan...
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| Language: | en en |
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2011
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| Online Access: | http://hdl.handle.net/1974/6891 |