Subcellular localization and trafficking of the RET receptor tyrosine kinase: implications for signalling and disease

Subcellular localization and trafficking of the RET receptor tyrosine kinase: implications for signalling and disease

The RET proto-oncogene encodes a receptor tyrosine kinase (RTK) that is widely expressed in neuroendocrine tissues and is essential for embryonic development of the kidney and enteric nervous system. Mutations leading to constitutive activation of the RET protein underlie various tumours of endocri...

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Bibliographic Details
Main Author: RICHARDSON, DOUGLAS
Other Authors: Queen's University (Kingston, Ont.). Theses (Queen's University (Kingston, Ont.))
Language:en
en
Published: 2009
Subjects:
RET
Intracellular Trafficking
Thyroid Carcinoma
Online Access:http://hdl.handle.net/1974/7478

Internet

http://hdl.handle.net/1974/7478

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