The Serum-‐ and Glucocorticoid-‐Inducible Kinase SGK1 and SGK3 Regulate hERG Channel Expression via Ubiquitin Ligase Nedd4-‐2 and GTPase Rab11
The rapidly activating delayed rectifier potassium channel (IKr) encoded by the human ether-a-go-go related gene (hERG) is a crucial component of cardiac repolarization of the action potential. The gating kinetics of the channel and the number of channels ...
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| Language: | en en |
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2013
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| Online Access: | http://hdl.handle.net/1974/8169 |