A novel TAFIa assay and its use to measure TAFI activation in vivo in primate models and the determination of the kinetics of TAFIa-catalyzed release of bound plasminogen from soluble fibrin degradation products

Thrombin-activatable fibrinolysis inhibitor (TAFI), also called procarboxypeptidase U (proCPU), is a plasma zymogen that can be activated by thrombin, the thrombin-thrombomodulin complex, or plasmin. The activated form of TAFI (TAFIa, CPU) removes C-terminal lysine residues of plasmin-modified fibr...

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Bibliographic Details
Main Author: Kim, Paula
Other Authors: Queen's University (Kingston, Ont.). Theses (Queen's University (Kingston, Ont.))
Format: Others
Language:en
en
Published: 2007
Subjects:
Online Access:http://hdl.handle.net/1974/863