Mechanisms of Hypoxia-Induced Neurovascular Remodeling in PlGF Knockout Mice
Due to the high metabolic demand and low capacity for energy storage of the brain, neurons are vitally reliant on a constant oxygen supply. Under chronic mild hypoxic conditions (10% oxygen), angiogenesis is induced in the brain in an attempt to restore tissue oxygen tension to normal levels. In b...
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Language: | en |
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2012
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Online Access: | http://hdl.handle.net/10393/20566 |