Mechanism and Therapeutic Potential of Statin-Mediated Inhibition of Tyrosine Kinase Receptors
Receptor tyrosine kinases (RTK) are key regulators of growth, differentiation and survival of epithelial cells and play a significant role in the development and progression of cancers derived from these tissues. In malignant cells, these receptors and their downstream signalling pathways are often...
Main Author: | |
---|---|
Language: | en |
Published: |
2011
|
Subjects: | |
Online Access: | http://hdl.handle.net/10393/20334 |