Mechanisms of Hypoxia-Induced Neurovascular Remodeling in PlGF Knockout Mice

Due to the high metabolic demand and low capacity for energy storage of the brain, neurons are vitally reliant on a constant oxygen supply. Under chronic mild hypoxic conditions (10% oxygen), angiogenesis is induced in the brain in an attempt to restore tissue oxygen tension to normal levels. In b...

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Bibliographic Details
Main Author: Freitas-Andrade, Moises
Language:en
Published: 2012
Subjects:
OGD
Online Access:http://hdl.handle.net/10393/20566