Exploiting Differential Endogenous MicroRNA Expression to Enhance Oncolytic Vesicular Stomatitis Virus Tumour Tropism
The creation of potent oncolytic viruses (OVs) suitable for the clinic may require new strategies in virus design. Replication-competent viruses facilitate a variety of approaches to achieving tumor specificity. Altered expression of microRNAs is a common hallmark of cancer that this thesis demonstr...
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| Language: | en |
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2010
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| Online Access: | http://hdl.handle.net/10393/19578 |