Towards a Microfluidics-based Nucleic Acid Biosensor Using Immobilized Quantum Dot – DNA Conjugates for FRET Detection of Target Oligonucleotides
The potential for an electrokinetically driven, FRET-based microfluidic biosensor for SNP discrimination has been explored. The method functionalized the glass wall of a PDMS/glass microfluidics channel with multidentate thiol ligands to noncovalently immobilize MPA capped CdSe/ZnS QDs. Single str...
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| Language: | en_ca |
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2009
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| Online Access: | http://hdl.handle.net/1807/17498 |