Soluble Globotriaosylceramide as a Potential Systemic and Local Inhibitor of HIV Infection
Previously we have identified the glycosphingolipid globotriaosylceramide (Gb3/Pk) as an inhibitor and resistance factor against HIV-1 infection in vitro. Here we show that a novel, soluble, completely synthetic Gb3 analogue, FSLGb3, inhibits infection of X4 strains of HIV-1 in the Jurkat T-cell li...
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| Language: | en_ca |
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2009
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| Online Access: | http://hdl.handle.net/1807/17511 |