Role of Distal Airway Epithelial Glucocorticoid-Glucocorticoid Receptor Signalling in Mouse Lung in Late Gestation

Glucocorticoid (GC) signalling via the GC receptor (GR) regulates many aspects of lung development. To determine the need for epithelial GC-GR signalling, triple transgenic (TT) mice with doxycycline (dox) – inducible suppression of GR exclusively in the distal lung epithelium (DLE) were created. Fo...

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Bibliographic Details
Main Author: Manwani, Neetu
Other Authors: Sweezey, Neil
Language:en_ca
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/1807/17697