The Role of ATM in Promoting Normal T cell Development and Preventing T Cell Leukemogenesis
The immune system recognizes and eliminates an enormous array of pathogens due to the diverse antigen receptor repertoire of T and B lymphocytes. However, the development of lymphocytes bearing receptors with unique specificities requires the generation of programmed double strand breaks (DSB) coupl...
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| Language: | en_ca |
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2009
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| Online Access: | http://hdl.handle.net/1807/17799 |