Modulation of the M2 Muscarinic Cholinergic Receptor by Cholesterol

M2 muscarinic receptor extracted from Sf9 cells in cholate-NaCl differs from that extracted from porcine sarcolemmal membranes. Whereas the latter has been shown to exhibit non-competitive effects in the binding of N-methylscopolamine (NMS) and quinuclidinylbenzilate (QNB), which can be explained i...

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Bibliographic Details
Main Author: Colozo, Alejandro
Other Authors: James, Wells
Language:en_ca
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/1807/19026