Orchestration of the DNA Damage Checkpoint Response through the Regulation of the Protein Kinase Rad53
In order to maintain genome stability, DNA damage needs to be detected and repaired in a timely fashion. To cope with damaged DNA, cells have evolved mechanisms termed "checkpoints", where, upon damage, cells initiate a signal transduction cascade that results in the slowing or halting of...
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| Language: | en_ca |
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2009
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| Online Access: | http://hdl.handle.net/1807/19097 |