Intracellular Signaling Pathways Regulating Hepatic Apolipoprotein B100 Production: Roles of Mitogen-activated Protein Kinases (MAPKs) and Inhibitor of NFkappaB Kinase (IKK)-NFkappaB

Apolipoprotein B100 (apoB), the structural protein component of triglyceride-rich very low density lipoprotein (VLDL) and atherogenic low density lipoprotein, is considered an important risk indicator of atherosclerosis. In insulin resistant states, hepatic overproduction of apoB leads to metabolic...

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Bibliographic Details
Main Author: Tsai, Julie
Other Authors: Adeli, Khosrow
Language:en_ca
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/1807/19239