Multidrug Resistance Protein 1 (MDR1) and Glycosphingolipids Biosynthesis: Advantages for Therapeutics

ABC drug transporter, MDR1, is a drug flippase that moves a variety of hydrophobic molecules from the inner to the outer leaflet of the plasma membrane. We have previously reported that MDR1 can function as a glycolipid flippase, being one of the mechanisms responsible for the translocation of gluco...

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Bibliographic Details
Main Author: De Rosa, Maria Fabiana
Other Authors: Lingwood, Clifford A.
Language:en_ca
Published: 2009
Subjects:
Online Access:http://hdl.handle.net/1807/19262