Activation of Chloride Channels with the Anti-parasitic Agent Ivermectin Induces Membrane Hyperpolarization and Cell Death in Leukemia Cells
FDA-approved drugs with previously unrecognized anti-cancer activity could be rapidly repurposed for this new indication. We compiled a library of such off-patent drugs to screen four leukemia cell lines and identified the anti-parasitic agent ivermectin that induced cell death at low micromolar co...
Main Author: | Sharmeen, Sumaiya |
---|---|
Other Authors: | Schimmer, Aaron D. |
Language: | en_ca |
Published: |
2010
|
Subjects: | |
Online Access: | http://hdl.handle.net/1807/24641 |
Similar Items
-
Activation of Chloride Channels with the Anti-parasitic Agent Ivermectin Induces Membrane Hyperpolarization and Cell Death in Leukemia Cells
by: Sharmeen, Sumaiya
Published: (2010) -
FCHSD2 Regulates Cell Death and Cell Adhesion
by: Sue, Stephanie Louise
Published: (2010) -
FCHSD2 Regulates Cell Death and Cell Adhesion
by: Sue, Stephanie Louise
Published: (2010) -
Efficiency of parenteral and oral ivermectin treatment on parasites in reindeer
by: T. Soveri, et al.
Published: (1990-09-01) -
Genetic and Microenvironmental Effects on Friend Murine Leukemia Virus-induced Erythroleukemia
by: Haeri, Mehran
Published: (2011)