Site-specific Facilitation or Inhibition of Dopamine-reward by Viral Transfection of M5 Muscarinic Receptors in the Tegmentum of M5 Knockout Mice
Knockdown of the M5 acetylcholine muscarinic receptor in the ventral tegmental area (VTA) reduces brain-stimulation reward sensitivity in rats. Knockout (KO) of the M5 receptor in mice reduces morphine-induced dopamine efflux, locomotion, conditionedplace- preference, and mating-induced 30-110 kHz u...
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| Language: | en_ca |
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2010
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| Online Access: | http://hdl.handle.net/1807/24647 |