Mechanisms Underlying Cardioprotective Effects of Glucagon like Peptide-1 in Ischemia-reperfusion Injury

Cardioprotective effects of glucagon-like peptide-1 (GLP-1), the GLP-1 receptor (GLP-1R) agonist exendin-4 (Ex-4), and GLP-1(9-36), a cleavage product of GLP-1, were examined in ischemia-reperfusion (I/R) models of both isolated mouse hearts and cultured cardiac myocytes (CMs) using both wild-type (...

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Bibliographic Details
Main Author: Ban, Kiwon
Other Authors: Husain, Mansoor
Language:en_ca
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1807/24675