The Protective Role of the Angiopoetin-1 - Tie2 System in Transgenic Models of Pulmonary Arterial Hypertension
The role of the Angiopoietin-1 (Ang1)-Tie2 pathway in pulmonary arterial hypertension (PAH) is controversial, with one group suggesting that increased Ang1-Tie2 activity may even play a causal role in PAH progression. However, Ang1 has been well-characterized as a homeostatic factor, which prevents...
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| Language: | en_ca |
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2010
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| Online Access: | http://hdl.handle.net/1807/24788 |