Regulation of Telomerase by DNA and Protein Interactions

In most eukaryotes, chromosomes ends are protected by telomeres which are formed by repetitive DNA, specialized binding proteins, and higher order structures. Telomeres become shorter following replication due to the positioning and degradation of terminal RNA primers, as well as resection by nuclea...

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Bibliographic Details
Main Author: Sealey, David Charles Fitzgerald
Other Authors: Harrington, Lea
Language:en_ca
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1807/24874