A Phage Display System to Profile the DNA-binding Specificities of C2H2 Zinc Fingers

A Phage Display System to Profile the DNA-binding Specificities of C2H2 Zinc Fingers

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Knowing the sequence specificities of transcription factors allows us to surmise their functions and establish their regulatory roles in genomes. The most common DNA-binding domain among eukaryotic transcription factors is the Cys2His2 zinc finger domain; however, despite their prevalence, the speci...

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Bibliographic Details
Main Author: Lam, Kathy
Other Authors: Hughes, Timothy R.
Language:en_ca
Published: 2010
Subjects:
C2H2
zinc fingers
phage display
modular
DNA-binding specificity
0307
Online Access:http://hdl.handle.net/1807/25742

Internet

http://hdl.handle.net/1807/25742

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