Hypoxia Suppresses DNA Repair: Implications for Cancer Progression and Treatment

Acute and chronic hypoxia exists within the microenvironment of solid tumours and drives therapy resistance, genetic instability and metastasis. Despite its importance in solid tumour progression, very little is known regarding the functional consequences of hypoxia-mediated changes in the expressio...

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Bibliographic Details
Main Author: Chan, Norman
Other Authors: Bristow, Robert
Language:en_ca
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/1807/26136