The Role of the p53 Tumour Suppressor Protein in Relation to the Sensing of Ionizing Radiation-induced DNA Double-strand Breaks
Our cells are constantly dealing with DNA damage generated by endogenous cellular activity (e.g. DNA replication) and exogenous agents (e.g. ultraviolet and ionizing radiation (IR)). The cellular stress response to DNA damage requires strict co-ordination between cell cycle checkpoint control and DN...
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Language: | en_ca |
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2010
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Online Access: | http://hdl.handle.net/1807/26447 |