Growth Factor Dependent Co-receptor Function of Neuropilins in Breast Carcinoma
Neuropilin (Nrp) overexpression is correlated with increased invasion and metastasis in many epithelial carcinomas including breast cancer. The exact molecular mechanism of how Nrp promotes cancer cell tumourigenicity is unknown. Nrp is a coreceptor for VEGF, hepatocyte growth factor (HGF), and also...
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| Language: | en_ca |
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2011
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| Online Access: | http://hdl.handle.net/1807/29532 |