Rac2 is Required for Formation of Extracellular Traps in Neutrophils

Recently, it was found that pathogens are trapped and killed by neutrophil extracellular traps (NETs). The role of Rac small GTPases is explored in the formation of NET using neutrophils lacking Rac1, Rac2 or both isoforms. NET formation was observed in both wild-type and Rac1-null neutrophils. In c...

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Bibliographic Details
Main Author: Lim, Byung Hyun
Other Authors: Glogauer, Michael
Language:en_ca
Published: 2011
Subjects:
Rac
Online Access:http://hdl.handle.net/1807/29592