The Role of Differential Phosphorylation of the Retinoblastoma Protein in Regulating Cell Proliferation and Elastogenesis

The Role of Differential Phosphorylation of the Retinoblastoma Protein in Regulating Cell Proliferation and Elastogenesis

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Previous studies suggest that the IGF-I stimulates the elastin gene transcription through the unique responsive sequence on the elastin promoter, which is a putative retinoblastoma control element (RCE). This site interacts with (Sp)-family transcription factors whose delivery is mediated by the re...

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Bibliographic Details
Main Author: Sen, Sanjana
Other Authors: Hinek, Aleksander
Language:en_ca
Published: 2011
Subjects:
Elastin
Retinoblastoma protein
Cell proliferation
Retinoblastoma control element
Cyclin E
Cyclin D
cdk-2
cdk-4
Costello Syndrome
Serine 780
Threonine 821
Elastin gene promoter
Sp-1
0307
Online Access:http://hdl.handle.net/1807/29617

Internet

http://hdl.handle.net/1807/29617

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