Mechanism of MicroRNA miR-520g Pathogenesis in CNS-PNET
We recently discovered a high-level amplicon spanning the chr19q13.41 microRNA cluster in CNS Primitive Neuroectodermal Tumour, which results in striking upregulation of miR-520g. Constitutive over-expression of miR-520g in untransformed human neural stem cells enhanced cell growth, restricted diffe...
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| Language: | en_ca |
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2011
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| Online Access: | http://hdl.handle.net/1807/29622 |