Predicting Kinase Substrates using Conservation of Local Motif Density

Short linear motifs (SLM) play critical roles in cell signaling and are associated with important biochemical events such as phosphorylation, glycosylation, and other post translational modifications. The primary aim of this thesis is to develop a new computational method (“ConDens”) to predict kina...

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Bibliographic Details
Main Author: Lai, Chi-Wai Andy
Other Authors: Moses, Alan
Language:en_ca
Published: 2011
Subjects:
Online Access:http://hdl.handle.net/1807/31290