Predicting Kinase Substrates using Conservation of Local Motif Density
Short linear motifs (SLM) play critical roles in cell signaling and are associated with important biochemical events such as phosphorylation, glycosylation, and other post translational modifications. The primary aim of this thesis is to develop a new computational method (“ConDens”) to predict kina...
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Language: | en_ca |
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2011
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Online Access: | http://hdl.handle.net/1807/31290 |