Morphine-induced Locomotion Increases following Viral Transfection of M5 Muscarinic Receptor Genes in the Ventromedial Hypothalamus of Wild-type Mice
Excitatory M5 muscarinic acetylcholine receptors are expressed at the highest level in the brain, in the ventromedial hypothalamus (VMH). M5 knockout (KO) mice emit fewer ultrasonic vocalizations (USVs) during mating, and show 40-50% lesser morphine-induced locomotion as compared to wild-type (WT) m...
| Main Author: | |
|---|---|
| Other Authors: | |
| Language: | en_ca |
| Published: |
2011
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/1807/31359 |