In situ Proximity Ligation-­based Analysis Reveals Aberrant Dimerization and Activation of Epidermal Growth Factor Receptors Prevalent in Glioblastoma Multiforme

In situ Proximity Ligation-­based Analysis Reveals Aberrant Dimerization and Activation of Epidermal Growth Factor Receptors Prevalent in Glioblastoma Multiforme

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Aberrations in Epidermal Growth Factor Receptor (EGFR/ErbB1) signalling are the most common oncogenic stimuli in human glioblastoma multiforme (GBM). Interactions between mutant and wildtype ErbB family members in GBMs are of biological and potential therapeutic importance. In this thesis, we descri...

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Bibliographic Details
Main Author: Gajadhar, Aaron
Other Authors: Guha, Abhijit
Language:en_ca
Published: 2011
Subjects:
EGFR
Glioblastoma multiforme
dimerization
activation
0760
Online Access:http://hdl.handle.net/1807/31755

Internet

http://hdl.handle.net/1807/31755

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