Identification and Characterization of Novel Components in UNC-6/Netrin Signaling
UNC-6/Netrin guides circumferential migrations along the dorso-ventral axis in C.elegans. Its receptors, UNC-40/DCC and UNC-5, mediate both attraction and repulsion of migrating cells or growth cones from sources of UNC-6. seu-2(ev523)and seu-3(ev555) (suppressor of ectopic unc-5) were identified as...
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Language: | en_ca |
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2011
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Online Access: | http://hdl.handle.net/1807/31902 |