Regulating BCA2: An Investigation into E3 Ligase Activity
The BCA2 E3 ligase is expressed in a majority of invasive breast cancers. BCA2 has inherent autoubiquitination activity which contributes to cell migration and proliferation processes. Here, ten novel BCA2 binding proteins were found using yeast and bacterial screening. Two of which were human ho...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/32226 |