Elucidating the Interaction between the Molecular Chaperone Hsp104 and the Yeast Prion Sup35

Hsp104 is a protein remodeling factor that is crucially important for induced thermotolerance and prion propagation in yeast. Recent work demonstrates that Hsp104 is able to directly recognize and interact with synthetic polypeptide substrates, and that this interaction is dependent on the amino aci...

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Bibliographic Details
Main Author: Helsen, Christopher W
Other Authors: Glover, John R.
Language:en_ca
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1807/32308