Syk Inhibition Attenuates Airway Hyperresponsiveness in a Murine Model of Asthma and Exacerbation by Air Pollution
Airway hyperresponsiveness (AHR) is a cardinal feature of asthma that is aggravated by environmental air pollution (EAP). Splenocyte tyrosine kinase Syk has been associated with asthma pathogenesis. Therefore, we sought to investigate the effect of Syk inhibition on AHR and its exacerbation by EAP....
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/33357 |