A Journey down the Cell Death Pathway of Mitochondria-targeted Chlorambucil
Our lab recently demonstrated that retargeting an alkylating agent, chlorambucil (Cbl), to the mitochondrion is a viable strategy to restore drug activity and overcome drug resistance in cancer. The mechanism of action of the mitochondria-targeted chlorambucil (mt-Cbl) was studied using a cervical...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/33466 |