Analysis of Somatic Copy Number Gains in Pancreatic Ductal Adenocarcinoma Implicates ECT2 as a Candidate Therapeutic Target

This study presents an integrated analysis of pancreatic ductal adenocarcinomas (PDACs) for identification of putative cancer driver genes in somatic copy number gains (SCNGs). SCNG data on 60 PDAC genomes was extracted to identify 756 genes, mapping to 20 genomic loci that are recurrently gained. T...

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Bibliographic Details
Main Author: Samuel, Nardin
Other Authors: Hudson, Thomas J.
Language:en_ca
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1807/33516