Protein Folding and Dynamics of Calmodulin via 19F-NMR

Calmodulin (CaM) is a ubiquitous calcium sensor protein which binds and activates a variety of enzymes involved in cell signaling pathways. In its calcium loaded state, CaM is extremely resistant to heat denaturation, with a melting temperature (Tm) of around 115°C. In this study, Xenopus laevis CaM...

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Bibliographic Details
Main Author: Thach, William
Other Authors: Prosser, Robert Scott
Language:en_ca
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/1807/33562