High Glucose-induced ROS Production is Mediated by c-Src in Mesangial Cells
The pathogenesis of diabetic nephropathy (DN) remains incompletely understood. In previous studies, we observed the activation of Tyr kinase Src by high glucose (HG) and showed that Src is required for MAPK activation and synthesis of collagen IV in cultured rat mesangial cells (MCs). Reactive oxyge...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/33753 |