Elucidating the Role of Endothelin-2 (ET-2) in Inherited Photoreceptor Degenerations and the Indirect Effects of Systemic ET-2 Loss
Inherited photoreceptor degenerations (IPDs) are the most common monogenic cause of blindness in humans. To discover genes that may influence the risk of death in IPDs, microarray studies were used, and ET-2 was identified as the most differentially expressed transcript. ET-2 mRNA was 32-fold (p<...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/33801 |