Identification and Verification of Candidate Biomarkers for Down Syndrome and Discovery of Dysregulated Molecular Pathways in Amniocytes by Proteomics Approaches
Down syndrome (DS), caused by an extra chromosome 21, affects 1 in 750 live births, and is characterized by cognitive impairment as well as several congenital defects. Currently, little is known about the molecular pathogenesis of DS and no direct genotype-phenotype relationship has yet been confirm...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/33873 |