Investigating the Role of PHIP1 in Breast Cancer
PHIP1 is a novel downstream transcriptional co-regulator of insulin-like growth factor-I receptor (IGF-IR), a tyrosine kinase receptor that is often elevated and autophosphorylated in breast cancer. In this study, I show that PHIP1 is upregulated in MCF10A cells stably overexpressing IGF-IR signalin...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/35154 |