Exploration of Peptide Recognition using Directed Evolution of the PDZ Domain Fold
The PDZ domain family is one of the most abundant peptide recognition modules in metazoan proteomes. Characterization of natural PDZ domains has provided insight into the structural basis and diversity of peptide recognition by this fold. In order to test the limits of the current model, I evolved s...
| Main Author: | |
|---|---|
| Other Authors: | |
| Language: | en_ca |
| Published: |
2013
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/1807/35648 |