Abrogation of the Retinoblastoma Pathway Defines Clinical Outcome in High Grade Serous Carcinoma
High Grade Serous Carcinoma is the most aggressive tubal/ovarian histotype. The Rb pathway, which functions to preserve cell cycle regulation and genomic stability, is frequently deregulated in HGSC. The aim of this study was to identify non-redundant mechanisms of Rb pathway deregulation with clini...
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| Language: | en_ca |
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2012
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| Online Access: | http://hdl.handle.net/1807/42403 |